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Gene : ARNTL Homo sapiens

Name  ? aryl hydrocarbon receptor nuclear translocator like Cytological Location  11p15.3
Brief Description  aryl hydrocarbon receptor nuclear translocator like
Description  The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
  • synonyms:
  • TIC,
  • HGNC:701,
  • basic helix-loop-helix family member e5,
  • BMAL1,
  • JAP3,
  • OTTHUMG00000150623,
  • ARNTL,
  • BMAL1c,
  • PASD3,
  • uc001mkp.4,
  • PAS domain containing 3,
  • MOP3,
  • NM_001178,
  • bHLHe5,
  • PASD3,
  • JAP3,
  • bHLHe5,
  • D89722,
  • BMAL1,
  • brain and muscle ARNT-like 1,
  • MOP3
  • identifiers:
  • 406,
  • ENSG00000133794,
  • ARNTL

Genome feature

Region: gene ? Length: 110717  
Location: 11:13276552-13387268 Cyto location: 11p15.3


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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Other

320 SN Ps

5 Cross References

17 Data Sets

11 Homologues

0 Located Features

97 Rna Seq Results