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Gene : CD180 Homo sapiens

Name  ? CD180 molecule Cytological Location  5q12.3
Brief Description  CD180 molecule
Description  CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq, Jul 2008]
  • synonyms:
  • RP105,
  • Ly78,
  • CD180,
  • LY64,
  • NM_005582,
  • RP105,
  • lymphocyte antigen 64 (mouse) homolog, radioprotective, 105kD,
  • CD180 antigen,
  • uc003juy.3,
  • Ly78,
  • HGNC:6726,
  • D83597,
  • OTTHUMG00000131229,
  • LY64
  • identifiers:
  • 4064,
  • ENSG00000134061,
  • CD180

Genome feature

Region: gene ? Length: 17187  
Location: 5:67179613-67196799 reverse strand Cyto location: 5q12.3


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

211 SN Ps

5 Cross References

16 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results