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Gene : ARRB1 Homo sapiens

Name  ? arrestin beta 1 Cytological Location  11q13.4
Brief Description  arrestin beta 1
Description  Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]
  • synonyms:
  • HGNC:711,
  • BC003636,
  • ARR1,
  • NM_004041,
  • OTTHUMG00000165444,
  • uc001owf.3,
  • arrestin, beta 1,
  • ARR1,
  • ARB1,
  • ARRB1,
  • arrestin 2
  • identifiers:
  • 408,
  • ENSG00000137486,
  • ARRB1

Genome feature

Region: gene ? Length: 91541  
Location: 11:75260122-75351662 reverse strand Cyto location: 11q13.4


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826 SN Ps

5 Cross References

17 Data Sets

11 Homologues

0 Located Features

97 Rna Seq Results