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Gene : ARRB2 Homo sapiens

Name  ? arrestin beta 2 Cytological Location  17p13.2
Brief Description  arrestin beta 2
Description  Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
  • synonyms:
  • uc002fyj.4,
  • DKFZp686L0365,
  • HGNC:712,
  • BARR2,
  • ARRB2,
  • BARR2,
  • OTTHUMG00000090759,
  • arrestin 3,
  • ARB2,
  • arrestin, beta 2,
  • NM_004313,
  • ARR2,
  • ARR2
  • identifiers:
  • 409,
  • ENSG00000141480,
  • ARRB2

Genome feature

Region: gene ? Length: 10882  
Location: 17:4710619-4721500 Cyto location: 17p13.2

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3740 SNPs

5 Cross References

16 Data Sets

9 Homologues

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97 Rna Seq Results