help  | about  | cite  | software

Gene : ASGR1 Homo sapiens

Name  ? asialoglycoprotein receptor 1 Cytological Location  17p13.1
Brief Description  asialoglycoprotein receptor 1
Description  This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
  • synonyms:
  • NM_001671,
  • HGNC:742,
  • HL-1,
  • CLEC4H1,
  • ASGPR,
  • ASGR1,
  • uc002ges.5,
  • CLEC4H1,
  • OTTHUMG00000102159,
  • ASGPR1
  • identifiers:
  • 432,
  • ENSG00000141505,
  • ASGR1

Genome feature

Region: gene ? Length: 5996  
Location: 17:7173431-7179426 reverse strand Cyto location: 17p13.1

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



50 SNPs

5 Cross References

16 Data Sets

17 Homologues

0 Located Features

97 Rna Seq Results