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Gene : ABCC1 Homo sapiens

Name  ? ATP binding cassette subfamily C member 1 Cytological Location  16p13.11
Brief Description  ATP binding cassette subfamily C member 1
Description  The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
  • synonyms:
  • NM_004996,
  • L05628,
  • MRP,
  • MRP1,
  • multidrug resistance associated protein 1,
  • uc010bvi.4,
  • DFNA77,
  • OTTHUMG00000048267,
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1,
  • MRP,
  • ABC29,
  • HGNC:51,
  • GS-X,
  • ABCC,
  • GS-X,
  • MRP1,
  • ABCC1
  • identifiers:
  • 4363,
  • ENSG00000103222,
  • ABCC1

Genome feature

Region: gene ? Length: 193447  
Location: 16:15949616-16143062 Cyto location: 16p13.11

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



894 SN Ps

5 Cross References

18 Data Sets

15 Homologues

0 Located Features

97 Rna Seq Results