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Gene : ABCC1 Homo sapiens

Name  ? ATP binding cassette subfamily C member 1 Cytological Location  16p13.11
Brief Description  ATP binding cassette subfamily C member 1
Description  The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
  • synonyms:
  • MRP,
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1,
  • ABCC,
  • multidrug resistance associated protein 1,
  • MRP,
  • ABC29,
  • GS-X,
  • L05628,
  • GS-X,
  • uc010bvi.4,
  • MRP1,
  • NM_004996,
  • OTTHUMG00000048267,
  • HGNC:51,
  • MRP1,
  • ABCC1
  • identifiers:
  • 4363,
  • ENSG00000103222,
  • ABCC1

Genome feature

Region: gene ? Length: 193447  
Location: 16:15949616-16143062 Cyto location: 16p13.11


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Disease

0 Diseases

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Expression

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894 SN Ps

5 Cross References

17 Data Sets

15 Homologues

0 Located Features

97 Rna Seq Results