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Gene : GET3 Homo sapiens

Name  ? guided entry of tail-anchored proteins factor 3, ATPase Cytological Location  19p13.13
Brief Description  guided entry of tail-anchored proteins factor 3, ATPase
Description  This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion. [provided by RefSeq, Oct 2011]
  • synonyms:
  • ASNA1,
  • golgi to ER traffic 3 homolog (S. cerevisiae),
  • ASNA-I,
  • TRC40,
  • U60276,
  • HGNC:752,
  • ARSA-I,
  • uc060uci.1,
  • ARSA-I,
  • OTTHUMG00000180355,
  • arsA (bacterial) arsenite transporter, ATP-binding, homolog 1,
  • ARSA1,
  • ASNA1,
  • transmembrane domain recognition complex, 40kDa,
  • GET3,
  • TRC40,
  • NM_004317
  • identifiers:
  • 439,
  • ENSG00000198356,
  • GET3

Genome feature

Region: gene ? Length: 11218  
Location: 19:12737106-12748323 Cyto location: 19p13.13


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Disease

0 Diseases

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72 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results