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Gene : GADD45B Homo sapiens

Name  ? growth arrest and DNA damage inducible beta Cytological Location  19p13.3
Brief Description  growth arrest and DNA damage inducible beta
Description  This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000180434,
  • DKFZP566B133,
  • MYD118,
  • myeloid differentiation primary response,
  • GADD45B,
  • uc002lwb.3,
  • MYD118,
  • growth arrest and DNA-damage-inducible beta,
  • NM_015675,
  • AF090950,
  • growth arrest and DNA-damage-inducible, beta,
  • HGNC:4096
  • identifiers:
  • 4616,
  • ENSG00000099860,
  • GADD45B

Genome feature

Region: gene ? Length: 2133  
Location: 19:2476127-2478259 Cyto location: 19p13.3

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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35 SN Ps

5 Cross References

16 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results