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Gene : ATP1A2 Homo sapiens

Name  ? ATPase Na+/K+ transporting subunit alpha 2 Cytological Location  1q23.2
Brief Description  ATPase Na /K transporting subunit alpha 2
Description  The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008]
  • synonyms:
  • ATPase, Na+/K+ transporting, alpha 2 polypeptide,
  • ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide,
  • ATP1A2,
  • HGNC:800,
  • FHM2,
  • AB018321,
  • MHP2,
  • migraine, hemiplegic 2,
  • MHP2,
  • sodium pump subunit alpha-2,
  • NM_000702,
  • OTTHUMG00000024080,
  • sodium/potassium-transporting ATPase subunit alpha-2,
  • sodium-potassium ATPase catalytic subunit alpha-2,
  • uc001fvc.4,
  • FHM2
  • identifiers:
  • 477,
  • ENSG00000018625,
  • ATP1A2

Genome feature

Region: gene ? Length: 27833  
Location: 1:160115759-160143591 Cyto location: 1q23.2


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Proteins

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SNPs

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Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Expression

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202 SN Ps

5 Cross References

19 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results