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Gene : ATP1B1 Homo sapiens

Name  ? ATPase Na+/K+ transporting subunit beta 1 Cytological Location  1q24.2
Brief Description  ATPase Na /K transporting subunit beta 1
Description  The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]
  • synonyms:
  • sodium-potassium ATPase subunit beta 1 (non-catalytic),
  • uc001gfr.2,
  • ATP1B,
  • sodium pump subunit beta-1,
  • U16799,
  • HGNC:804,
  • ATP1B1,
  • ATPase, Na+/K+ transporting, beta 1 polypeptide,
  • sodium/potassium-transporting ATPase subunit beta-1,
  • OTTHUMG00000034590,
  • NM_001677,
  • ATP1B
  • identifiers:
  • 481,
  • ENSG00000143153,
  • ATP1B1

Genome feature

Region: gene ? Length: 26030  
Location: 1:169106690-169132719 Cyto location: 1q24.2


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Disease

1 Diseases

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3756 SN Ps

5 Cross References

19 Data Sets

17 Homologues

0 Located Features

97 Rna Seq Results