help  | about  | cite  | software

Gene : ATP5F1A Homo sapiens
Name  ? ATP synthase F1 subunit alpha Cytological Location  18q21.1
Brief Description  ATP synthase F1 subunit alpha
Description  This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16. [provided by RefSeq, Mar 2012]
  • synonyms:
  • hATP1,
  • COXPD22,
  • D14710,
  • OTTHUMG00000132637,
  • HEL-S-123m,
  • uc002lbt.1,
  • ORM,
  • ATPM,
  • ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle,
  • HGNC:823,
  • MOM2,
  • ATP5AL2,
  • ATP5A,
  • NM_004046,
  • ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 2, non-cardiac muscle-like 2,
  • ATP5F1A,
  • ATPM,
  • OMR,
  • ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle,
  • ATP5A1,
  • ATP5A1,
  • ORM,
  • hATP1,
  • OMR,
  • MC5DN4,
  • ATP5A,
  • ATP5AL2
  • identifiers:
  • 498,
  • ENSG00000152234,
  • ATP5F1A

Genome feature

Region: gene ? Length: 23980  
Location: 18:46080248-46104227 reverse strand Cyto location: 18q21.1


Paste the following link

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

9 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

9 Pathways

3740 SNPs

5 Cross References

19 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results





Funding: InterMine has been developed principally through support of the Wellcome Trust. Complementary projects have been funded by the NIH/NHGRI and the BBSRC.

An ELIXIR-UK resource

© 2002 - 2019 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom