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Gene : ATP5F1A Homo sapiens

Name  ? ATP synthase F1 subunit alpha Cytological Location  18q21.1
Brief Description  ATP synthase F1 subunit alpha
Description  This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16. [provided by RefSeq, Mar 2012]
  • synonyms:
  • ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle,
  • OTTHUMG00000132637,
  • ATP5A,
  • ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle,
  • ATP5A1,
  • uc002lbt.1,
  • NM_004046,
  • ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 2, non-cardiac muscle-like 2,
  • ATP5F1A,
  • MC5DN4,
  • D14710,
  • ATPM,
  • ORM,
  • COXPD22,
  • ATPM,
  • HEL-S-123m,
  • hATP1,
  • hATP1,
  • OMR,
  • OMR,
  • ATP5A1,
  • ATP5AL2,
  • ATP5AL2,
  • MOM2,
  • ATP5A,
  • ORM,
  • HGNC:823
  • identifiers:
  • 498,
  • ENSG00000152234,
  • ATP5F1A

Genome feature

Region: gene ? Length: 23986  
Location: 18:46080248-46104233 reverse strand Cyto location: 18q21.1


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2 Diseases

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3756 SN Ps

5 Cross References

20 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results