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Gene : CD207 Homo sapiens

Name  ? CD207 molecule Cytological Location  2p13.3
Brief Description  CD207 molecule
Description  The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010]
  • synonyms:
  • HGNC:17935,
  • CLEC4K,
  • CD207,
  • CD207 antigen, langerin,
  • AJ242859,
  • CD207 molecule, langerin,
  • NM_015717,
  • OTTHUMG00000153176,
  • uc002shg.4,
  • Langerin,
  • CLEC4K
  • identifiers:
  • 50489,
  • ENSG00000116031,
  • CD207

Genome feature

Region: gene ? Length: 35540  
Location: 2:70825248-70860787 reverse strand Cyto location: 2p13.3

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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3740 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results