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Gene : PAK1 Homo sapiens

Name  ? p21 (RAC1) activated kinase 1 Cytological Location  11q13.5-q14.1
Brief Description  p21 (RAC1) activated kinase 1
description  This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
  • synonyms:
  • p21 protein (Cdc42/Rac)-activated kinase 1,
  • OTTHUMG00000165138,
  • NM_002576,
  • p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related),
  • U51120,
  • STE20 homolog, yeast,
  • p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast),
  • uc001oyh.5,
  • PAKalpha,
  • PAK1,
  • HGNC:8590,
  • identifiers:
  • 5058,
  • ENSG00000149269,
  • PAK1

Genome feature

Region: gene ? Length: 192943  
Location: 11:77322015-77514957 reverse strand Cyto location: 11q13.5-q14.1

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56 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Ontology

Gene --> GO terms.



56 Pathways

3756 SN Ps

5 Cross References

20 Data Sets

53 Homologues

2 Located Features

97 Rna Seq Results