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Gene : DHH Homo sapiens

Name  ? desert hedgehog signaling molecule Cytological Location  12q13.12
Brief Description  desert hedgehog signaling molecule
Description  This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq, May 2010]
  • synonyms:
  • desert hedgehog,
  • MGC35145,
  • HGNC:2865,
  • AB010994,
  • NM_021044,
  • HHG-3,
  • uc001rtf.4,
  • SRXY7,
  • desert hedgehog (Drosophila) homolog,
  • OTTHUMG00000170408,
  • GDXYM,
  • DHH,
  • HHG-3
  • identifiers:
  • 50846,
  • ENSG00000139549,
  • DHH

Genome feature

Region: gene ? Length: 8146  
Location: 12:49086656-49094801 reverse strand Cyto location: 12q13.12


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Proteins

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SNPs

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Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

202 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results