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Gene : F11R Homo sapiens

Name  ? F11 receptor Cytological Location  1q23.3
Brief Description  F11 receptor
Description  Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
  • synonyms:
  • AF111713,
  • CD321,
  • uc009wtt.4,
  • JAM-A,
  • JAM1,
  • JCAM,
  • NM_016946,
  • JAM-1,
  • JAMA,
  • JCAM,
  • JAM1,
  • HGNC:14685,
  • OTTHUMG00000028602,
  • PAM-1,
  • KAT,
  • JAM,
  • JAMA,
  • F11R,
  • junctional adhesion molecule 1,
  • CD321,
  • PAM-1
  • identifiers:
  • 50848,
  • ENSG00000158769,
  • F11R

Genome feature

Region: gene ? Length: 25942  
Location: 1:160995211-161021152 reverse strand Cyto location: 1q23.3

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3753 SN Ps

5 Cross References

17 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results