help  | about  | cite  | software

Gene : COPS4 Homo sapiens

Name  ? COP9 signalosome subunit 4 Cytological Location  4q21.22
Brief Description  COP9 signalosome subunit 4
Description  This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • synonyms:
  • AF100757,
  • CSN4,
  • SGN4,
  • NM_001258006,
  • OTTHUMG00000130298,
  • COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 4,
  • COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis),
  • CSN4,
  • COPS4,
  • HGNC:16702,
  • uc003hoa.4
  • identifiers:
  • 51138,
  • ENSG00000138663,
  • COPS4

Genome feature

Region: gene ? Length: 40636  
Location: 4:83035183-83075818 Cyto location: 4q21.22


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

240 SN Ps

5 Cross References

15 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results