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Gene : COPS4 Homo sapiens

Name  ? COP9 signalosome subunit 4 Cytological Location  4q21.22
Brief Description  COP9 signalosome subunit 4
Description  This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • synonyms:
  • NM_001258006,
  • HGNC:16702,
  • uc003hoa.4,
  • COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 4,
  • SGN4,
  • COPS4,
  • COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis),
  • CSN4,
  • CSN4,
  • AF100757,
  • OTTHUMG00000130298
  • identifiers:
  • 51138,
  • ENSG00000138663,
  • COPS4

Genome feature

Region: gene ? Length: 40636  
Location: 4:83035183-83075818 Cyto location: 4q21.22

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Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



240 SNPs

5 Cross References

15 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results