help  | about  | cite  | software

Gene : GP6 Homo sapiens

Name  ? glycoprotein VI platelet Cytological Location  19q13.42
Brief Description  glycoprotein VI platelet
Description  This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
  • synonyms:
  • uc002qil.4,
  • NM_001083899,
  • GPVI,
  • GPVI,
  • HGNC:14388,
  • AB035073,
  • glycoprotein VI (platelet),
  • GP6,
  • GPIV,
  • platelet glycoprotein VI,
  • BDPLT11,
  • OTTHUMG00000159709
  • identifiers:
  • 51206,
  • ENSG00000088053,
  • GP6

Genome feature

Region: gene ? Length: 24560  
Location: 19:55013705-55038264 reverse strand Cyto location: 19q13.42


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

3753 SN Ps

5 Cross References

19 Data Sets

1 Homologues

0 Located Features

97 Rna Seq Results