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Gene : ABI3 Homo sapiens

Name  ? ABI family member 3 Cytological Location  17q21.32
Brief Description  ABI family member 3
Description  This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  • synonyms:
  • NM_016428,
  • ABI family, member 3,
  • AB037886,
  • uc002iop.1,
  • SSH3BP3,
  • HGNC:29859,
  • NESH,
  • OTTHUMG00000161306,
  • NESH,
  • ABI3,
  • SSH3BP3
  • identifiers:
  • 51225,
  • ENSG00000108798,
  • ABI3

Genome feature

Region: gene ? Length: 12644  
Location: 17:49210582-49223225 Cyto location: 17q21.32

Uni Prot Comments Displayer

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Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Structure Displayer

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

41 SNPs

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results