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Gene : ACTL6B Homo sapiens

Name  ? actin like 6B Cytological Location  7q22.1
Brief Description  actin like 6B
Description  The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
  • synonyms:
  • BAF53B,
  • uc003uvy.4,
  • ACTL6B,
  • DEE76,
  • ACTL6,
  • actin-like 6,
  • HGNC:160,
  • ACTL6,
  • AB015906,
  • BAF53B,
  • EIEE76,
  • arpNalpha,
  • OTTHUMG00000159661,
  • NM_016188
  • identifiers:
  • 51412,
  • ENSG00000077080,
  • ACTL6B

Genome feature

Region: gene ? Length: 13352  
Location: 7:100643097-100656448 reverse strand Cyto location: 7q22.1

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2 Diseases

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12 SN Ps

5 Cross References

19 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results