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Gene : POLK Homo sapiens

Name  ? DNA polymerase kappa Cytological Location  5q13.3
Brief Description  DNA polymerase kappa
Description  This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. [provided by RefSeq, Sep 2016]
  • synonyms:
  • DINB1,
  • DINB1,
  • AB027564,
  • NM_016218,
  • DNA polymerase kappa,
  • DINP,
  • DINB protein,
  • polymerase (DNA directed) kappa,
  • DINP,
  • polymerase (DNA) kappa,
  • POLK,
  • POLQ,
  • OTTHUMG00000102107,
  • uc003kdw.4,
  • POLQ,
  • HGNC:9183
  • identifiers:
  • 51426,
  • ENSG00000122008,
  • POLK

Genome feature

Region: gene ? Length: 94513  
Location: 5:75511308-75605820 Cyto location: 5q13.3

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

15 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results