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Gene : GSKIP Homo sapiens

Name  ? GSK3B interacting protein Cytological Location  14q32.2
Brief Description  GSK3B interacting protein
Description  This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
  • synonyms:
  • GSK3beta interaction protein,
  • C14orf129,
  • uc031qqf.2,
  • GSKIP,
  • HSPC210,
  • chromosome 14 open reading frame 129,
  • C14orf129,
  • NM_016472,
  • OTTHUMG00000171420,
  • AF151044,
  • HGNC:20343
  • identifiers:
  • 51527,
  • ENSG00000100744,
  • GSKIP

Genome feature

Region: gene ? Length: 23839  
Location: 14:96363452-96387290 Cyto location: 14q32.2


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Proteins

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Disease

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Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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0 Pathways

3753 SN Ps

5 Cross References

15 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results