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Gene : CHMP3 Homo sapiens

Name  ? charged multivesicular body protein 3 Cytological Location  2p11.2
Brief Description  charged multivesicular body protein 3
Description  This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq, Nov 2010]
  • synonyms:
  • NEDF,
  • OTTHUMG00000153189,
  • uc002srj.4,
  • NEDF,
  • VPS24,
  • AF219226,
  • CHMP3,
  • VPS24,
  • CGI-149,
  • vacuolar protein sorting 24 (yeast),
  • CGI-149,
  • HGNC:29865,
  • NM_016079,
  • vacuolar protein sorting 24 homolog (S. cerevisiae)
  • identifiers:
  • 51652,
  • ENSG00000115561,
  • CHMP3

Genome feature

Region: gene ? Length: 60014  
Location: 2:86503430-86563443 reverse strand Cyto location: 2p11.2


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Disease

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3753 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results