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Gene : COQ3 Homo sapiens

Name  ? coenzyme Q3, methyltransferase Cytological Location  6q16.2
Brief Description  coenzyme Q3, methyltransferase
Description  Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008]
  • synonyms:
  • bA9819.1,
  • OTTHUMG00000015264,
  • NM_017421,
  • coenzyme Q3 homolog, methyltransferase (yeast),
  • HGNC:18175,
  • polyprenyldihydroxybenzoate methyltransferase,
  • uc003ppk.4,
  • AF193016,
  • coenzyme Q3 homolog, methyltransferase (S. cerevisiae),
  • bA9819.1,
  • COQ3,
  • UG0215E05,
  • identifiers:
  • 51805,
  • ENSG00000132423,
  • COQ3

Genome feature

Region: gene ? Length: 24823  
Location: 6:99369401-99394223 reverse strand Cyto location: 6q16.2

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0 Diseases

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333 SN Ps

5 Cross References

16 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results