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Gene : ATP6V1B2 Homo sapiens

Name  ? ATPase H+ transporting V1 subunit B2 Cytological Location  8p21.3
Brief Description  ATPase H transporting V1 subunit B2
Description  This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]
  • synonyms:
  • ATP6B2,
  • VPP3,
  • ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B, isoform 2,
  • OTTHUMG00000131073,
  • L35249,
  • ATP6B2,
  • DOOD,
  • ATP6V1B2,
  • VATB,
  • Vma2,
  • ATP6B1B2,
  • HO57,
  • ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 56/58kD, isoform 2,
  • Vma2,
  • VATB,
  • VPP3,
  • uc003wzp.4,
  • HGNC:854,
  • NM_001693,
  • ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2,
  • ZLS2,
  • HO57
  • identifiers:
  • 526,
  • ENSG00000147416,
  • ATP6V1B2

Genome feature

Region: gene ? Length: 29478  
Location: 8:20197375-20226852 Cyto location: 8p21.3


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2 Diseases

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53 SN Ps

5 Cross References

20 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results