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Gene : ATP6V0C Homo sapiens

Name  ? ATPase H+ transporting V0 subunit c Cytological Location  16p13.3
Brief Description  ATPase H transporting V0 subunit c
Description  This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17. [provided by RefSeq, Nov 2010]
  • synonyms:
  • ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c,
  • ATP6C,
  • VATL,
  • ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16kD,
  • ATP6L,
  • ATP6C,
  • ATP6V0C,
  • ATPL,
  • Vma3,
  • Vma3,
  • OTTHUMG00000128865,
  • ATP6L,
  • M62762,
  • uc002cqn.4,
  • ATPL,
  • NM_001694,
  • HGNC:855,
  • VATL,
  • VPPC
  • identifiers:
  • 527,
  • ENSG00000185883,
  • ATP6V0C

Genome feature

Region: gene ? Length: 6493  
Location: 16:2513726-2520218 Cyto location: 16p13.3

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0 Diseases

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319 SNPs

5 Cross References

15 Data Sets

14 Homologues

0 Located Features

97 Rna Seq Results