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Gene : BCL11A Homo sapiens

Name  ? BAF chromatin remodeling complex subunit BCL11A Cytological Location  2p16.1
Brief Description  BAF chromatin remodeling complex subunit BCL11A
Description  This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_022893,
  • B-cell CLL/lymphoma 11A (zinc finger protein),
  • AJ404611,
  • OTTHUMG00000129420,
  • BCL11A-S,
  • BCL11A-L,
  • HGNC:13221,
  • uc002sae.2,
  • CTIP1,
  • HBFQTL5,
  • BCL11A-XL,
  • EVI9,
  • DILOS,
  • EVI9,
  • BCL11A-S,
  • HBFQTL5,
  • B cell CLL/lymphoma 11A,
  • CTIP1,
  • ZNF856,
  • ZNF856,
  • BCL11A-XL,
  • ecotropic viral integration site 9,
  • BCL11A-L,
  • BCL11A,
  • BCL11a-M,
  • BCL11A, BAF complex component
  • identifiers:
  • 53335,
  • ENSG00000119866,
  • BCL11A

Genome feature

Region: gene ? Length: 103135  
Location: 2:60450520-60553654 reverse strand Cyto location: 2p16.1


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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Proteins

Gene --> Proteins.

SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Gene --> GO terms.

 

Other

0 Pathways

421 SN Ps

5 Cross References

19 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results