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Gene : ATP6V1G2 Homo sapiens

Name  ? ATPase H+ transporting V1 subunit G2 Cytological Location  6p21.33
Brief Description  ATPase H transporting V1 subunit G2
Description  This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described. Read-through transcription also exists between this gene and the downstream DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (DDX39B) gene. [provided by RefSeq, Feb 2011]
  • synonyms:
  • VMA10,
  • Y14768,
  • ATP6G2,
  • Em:AC004181.3,
  • NG38,
  • ATP6V1G2,
  • ATP6G,
  • OTTHUMG00000166618,
  • ATP6G,
  • ATPase, H+ transporting, lysosomal (vacuolar proton pump),
  • NG38,
  • ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform 2,
  • NM_130463,
  • ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2,
  • ATP6G2,
  • Vma10,
  • HGNC:862,
  • uc021zuc.2
  • identifiers:
  • 534,
  • ENSG00000213760,
  • ATP6V1G2

Genome feature

Region: gene ? Length: 2299  
Location: 6:31544444-31546742 reverse strand Cyto location: 6p21.33


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32225 SN Ps

5 Cross References

15 Data Sets

6 Homologues

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97 Rna Seq Results