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Gene : POLD2 Homo sapiens

Name  ? DNA polymerase delta 2, accessory subunit Cytological Location  7p13
Brief Description  DNA polymerase delta 2, accessory subunit
Description  This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012]
  • synonyms:
  • OTTHUMG00000022909,
  • uc010kxz.5,
  • HGNC:9176,
  • polymerase (DNA) delta 2, accessory subunit,
  • NM_001127218,
  • Pol delta B subunit (p50),
  • polymerase (DNA directed), delta 2, regulatory subunit (50kD),
  • DNA polymerase delta subunit p50,
  • polymerase (DNA directed), delta 2, regulatory subunit 50kDa,
  • POLD2
  • identifiers:
  • 5425,
  • ENSG00000106628,
  • POLD2

Genome feature

Region: gene ? Length: 8989  
Location: 7:44114680-44123668 reverse strand Cyto location: 7p13


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Function

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49 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

49 Pathways

3753 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results