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Gene : POLE2 Homo sapiens

Name  ? DNA polymerase epsilon 2, accessory subunit Cytological Location  14q21.3
Brief Description  DNA polymerase epsilon 2, accessory subunit
Description  DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B). Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency. [provided by RefSeq, Jan 2017]
  • synonyms:
  • uc001wwu.4,
  • AF025840,
  • DPE2,
  • polymerase (DNA) epsilon 2, accessory subunit,
  • NM_002692,
  • POLE2,
  • OTTHUMG00000170813,
  • HGNC:9178,
  • DPE2,
  • polymerase (DNA directed), epsilon 2 (p59 subunit),
  • DNA polymerase epsilon subunit B
  • identifiers:
  • 5427,
  • ENSG00000100479,
  • POLE2

Genome feature

Region: gene ? Length: 44866  
Location: 14:49643552-49688417 reverse strand Cyto location: 14q21.3


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

202 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results