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Gene : FBXW5 Homo sapiens

Name  ? F-box and WD repeat domain containing 5 Cytological Location  9q34.3
Brief Description  F-box and WD repeat domain containing 5
Description  This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. [provided by RefSeq, Jul 2008]
  • synonyms:
  • Fbw5,
  • F-box and WD-40 domain protein 5,
  • BC014130,
  • MGC20962,
  • HGNC:13613,
  • FBXW5,
  • NM_018998,
  • Fbw5,
  • uc004cjx.4,
  • OTTHUMG00000020967,
  • DKFZP434B205
  • identifiers:
  • 54461,
  • ENSG00000159069,
  • FBXW5

Genome feature

Region: gene ? Length: 4340  
Location: 9:136940435-136944774 reverse strand Cyto location: 9q34.3

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0 Diseases

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435 SN Ps

5 Cross References

16 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results