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Gene : MED1 Homo sapiens

Name  ? mediator complex subunit 1 Cytological Location  17q12
Brief Description  mediator complex subunit 1
description  The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CRSP200,
  • NM_004774,
  • OTTHUMG00000133216,
  • RB18A,
  • TRAP220,
  • TRIP2,
  • DRIP230,
  • PBP,
  • CRSP1,
  • PBP,
  • L40366,
  • TRIP2,
  • TRAP220,
  • CRSP1,
  • MED1,
  • CRSP200,
  • RB18A,
  • uc002hrv.5,
  • DRIP230,
  • HGNC:9234,
  • DRIP205,
  • PPAR binding protein
  • identifiers:
  • 5469,
  • ENSG00000125686,
  • MED1

Genome feature

Region: gene ? Length: 46997  
Location: 17:39404285-39451281 reverse strand Cyto location: 17q12

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0 Diseases

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329 SN Ps

5 Cross References

17 Data Sets

5 Homologues

10 Located Features

97 Rna Seq Results