help  | about  | cite  | software

Gene : CTSA Homo sapiens

Name  ? cathepsin A Cytological Location  20q13.12
Brief Description  cathepsin A
Description  This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis. [provided by RefSeq, Nov 2015]
  • synonyms:
  • NGBE,
  • uc002xqh.4,
  • PPGB,
  • HGNC:9251,
  • GLB2,
  • OTTHUMG00000033078,
  • urinary kininase,
  • lysosomal carboxypeptidase A,
  • carboxypeptidase-L,
  • deamidase,
  • GSL,
  • carboxypeptidase C,
  • M22960,
  • NM_000308,
  • PPCA,
  • PPGB,
  • protective protein for beta-galactosidase (galactosialidosis),
  • lysosomal protective protein,
  • carboxypeptidase Y-like kininase,
  • GSL,
  • CTSA
  • identifiers:
  • 5476,
  • ENSG00000064601,
  • CTSA

Genome feature

Region: gene ? Length: 8677  
Location: 20:45890144-45898820 Cyto location: 20q13.12

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3756 SN Ps

5 Cross References

19 Data Sets

13 Homologues

0 Located Features

97 Rna Seq Results