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Gene : HERC6 Homo sapiens

Name  ? HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 Cytological Location  4q22.1
Brief Description  HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
Description  HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008]
  • synonyms:
  • NM_001165136,
  • FLJ20637,
  • HERC6,
  • AF336798,
  • uc011cdi.3,
  • HGNC:26072,
  • OTTHUMG00000160983,
  • hect domain and RLD 6
  • identifiers:
  • 55008,
  • ENSG00000138642,
  • HERC6

Genome feature

Region: gene ? Length: 64613  
Location: 4:88378485-88443097 Cyto location: 4q22.1


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Other

206 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results