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Gene : MACROH2A2 Homo sapiens

Name  ? macroH2A.2 histone Cytological Location  10q22.1
Brief Description  macroH2A.2 histone
Description  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and may participate in stable X chromosome inactivation. [provided by RefSeq, Oct 2015]
  • synonyms:
  • H2AFY2,
  • MACROH2A2,
  • AF336304,
  • H2AFY2,
  • macroH2A2,
  • NM_018649,
  • H2A histone family, member Y2,
  • H2A histone family member Y2,
  • uc001jqm.4,
  • HGNC:14453,
  • OTTHUMG00000018396
  • identifiers:
  • 55506,
  • ENSG00000099284,

Genome feature

Region: gene ? Length: 59437  
Location: 10:70052846-70112282 Cyto location: 10q22.1

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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226 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results