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Gene : CHFR Homo sapiens

Name  ? checkpoint with forkhead and ring finger domains Cytological Location  12q24.33
Brief Description  checkpoint with forkhead and ring finger domains
Description  This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014]
  • synonyms:
  • NM_001161344,
  • HGNC:20455,
  • RNF196,
  • uc001ulf.3,
  • CHFR,
  • RNF116,
  • AK001658,
  • OTTHUMG00000167930,
  • RNF196,
  • FLJ10796
  • identifiers:
  • 55743,
  • ENSG00000072609,
  • CHFR

Genome feature

Region: gene ? Length: 55263  
Location: 12:132832356-132887618 reverse strand Cyto location: 12q24.33

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

3740 SNPs

5 Cross References

17 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results