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Gene : AXL Homo sapiens

Name  ? AXL receptor tyrosine kinase Cytological Location  19q13.2
Brief Description  AXL receptor tyrosine kinase
Description  The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  • synonyms:
  • Tyro7,
  • NM_001278599,
  • uc010ehj.5,
  • M76125,
  • HGNC:905,
  • UFO,
  • UFO,
  • OTTHUMG00000182727,
  • ARK,
  • JTK11,
  • AXL,
  • JTK11,
  • ARK,
  • Tyro7
  • identifiers:
  • 558,
  • ENSG00000167601,
  • AXL

Genome feature

Region: gene ? Length: 42544  
Location: 19:41219223-41261766 Cyto location: 19q13.2

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

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Gene --> GO terms.



856 SN Ps

5 Cross References

18 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results