help  | about  | cite  | software

Gene : ERBIN Homo sapiens

Name  ? erbb2 interacting protein Cytological Location  5q12.3
Brief Description  erbb2 interacting protein
Description  This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
  • synonyms:
  • ERBB2IP,
  • HGNC:15842,
  • NM_018695,
  • ERBIN,
  • uc003jui.3,
  • HEL-S-78,
  • ERBB2-interacting protein,
  • ERBB2IP,
  • densin-180-like protein,
  • OTTHUMG00000097808,
  • LAP2,
  • erbb2-interacting protein,
  • LAP2
  • identifiers:
  • 55914,
  • ENSG00000112851,

Genome feature

Region: gene ? Length: 155993  
Location: 5:65926554-66082546 Cyto location: 5q12.3

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



454 SN Ps

5 Cross References

18 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results