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Gene : DMAP1 Homo sapiens

Name  ? DNA methyltransferase 1 associated protein 1 Cytological Location  1p34.1
Brief Description  DNA methyltransferase 1 associated protein 1
Description  This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
  • synonyms:
  • AB037846,
  • SWC4,
  • OTTHUMG00000007577,
  • DMAP1,
  • MEAF2,
  • FLJ11543,
  • DNMTAP1,
  • DNMTAP1,
  • NM_019100,
  • MEAF2,
  • SWC4,
  • HGNC:18291,
  • uc001clq.2,
  • EAF2,
  • KIAA1425,
  • EAF2,
  • DNMAP1,
  • DNMAP1
  • identifiers:
  • 55929,
  • ENSG00000178028,
  • DMAP1

Genome feature

Region: gene ? Length: 7203  
Location: 1:44213471-44220673 Cyto location: 1p34.1


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Disease

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3753 SN Ps

5 Cross References

15 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results