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Gene : BTNL2 Homo sapiens

Name  ? butyrophilin like 2 Cytological Location  6p21.32
Brief Description  butyrophilin like 2
Description  This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. [provided by RefSeq, May 2017]
  • synonyms:
  • OTTHUMG00000031102,
  • HSBLMHC1,
  • HSBLMHC1,
  • AF186588,
  • BTL-II,
  • SS2,
  • uc063nqv.1,
  • NM_019602,
  • butyrophilin-like 2 (MHC class II associated),
  • BTN7,
  • HGNC:1142,
  • BTN7,
  • butyrophilin-like 2,
  • BTL-II,
  • BTNL2
  • identifiers:
  • 56244,
  • ENSG00000204290,
  • BTNL2

Genome feature

Region: gene ? Length: 15541  
Location: 6:32393339-32408879 reverse strand Cyto location: 6p21.32


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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

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Other

3756 SN Ps

4 Cross References

14 Data Sets

22 Homologues

0 Located Features

97 Rna Seq Results