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Gene : CTPS2 Homo sapiens

Name  ? CTP synthase 2 Cytological Location  Xp22.2
Brief Description  CTP synthase 2
Description  The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  • synonyms:
  • uc004cxm.5,
  • CTP synthase II,
  • AF086422,
  • HGNC:2520,
  • CTPS2,
  • OTTHUMG00000021193,
  • NM_019857
  • identifiers:
  • 56474,
  • ENSG00000047230,
  • CTPS2

Genome feature

Region: gene ? Length: 124919  
Location: X:16587999-16712917 reverse strand Cyto location: Xp22.2


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

183 SN Ps

5 Cross References

16 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results