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Gene : HTRA1 Homo sapiens

Name  ? HtrA serine peptidase 1 Cytological Location  10q26.13
Brief Description  HtrA serine peptidase 1
Description  This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008]
  • synonyms:
  • L56,
  • IGFBP5-protease,
  • protease, serine, 11 (IGF binding),
  • HGNC:9476,
  • ARMD7,
  • uc001lgj.2,
  • HtrA,
  • OTTHUMG00000019186,
  • PRSS11,
  • HtrA,
  • ARMD7,
  • HTRA1,
  • ORF480,
  • NM_002775,
  • AF097709,
  • PRSS11
  • identifiers:
  • 5654,
  • ENSG00000166033,
  • HTRA1

Genome feature

Region: gene ? Length: 53355  
Location: 10:122461553-122514907 Cyto location: 10q26.13

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Gene -> HPO annotation (Human Phenotype Ontology)

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3 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Ontology

Gene --> GO terms.



482 SN Ps

5 Cross References

19 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results