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Gene : AZU1 Homo sapiens

Name  ? azurocidin 1 Cytological Location  19p13.3
Brief Description  azurocidin 1
Description  Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Nov 2015]
  • synonyms:
  • HBP,
  • cationic antimicrobial protein 37,
  • HUMAZUR,
  • HGNC:913,
  • AZU1,
  • hHBP,
  • neutrophil azurocidin,
  • CAP37,
  • HBP,
  • NAZC,
  • heparin-binding protein,
  • AZU,
  • AZAMP,
  • X58794,
  • uc002lpz.2,
  • AZU,
  • OTTHUMG00000187023,
  • AZAMP,
  • NM_001700,
  • HUMAZUR,
  • CAP37,
  • NAZC
  • identifiers:
  • 566,
  • ENSG00000172232,
  • AZU1

Genome feature

Region: gene ? Length: 4182  
Location: 19:827837-832018 Cyto location: 19p13.3


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Disease

0 Diseases

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82 SN Ps

5 Cross References

15 Data Sets

0 Homologues

0 Located Features

97 Rna Seq Results