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Gene : CYP26B1 Homo sapiens

Name  ? cytochrome P450 family 26 subfamily B member 1 Cytological Location  2p13.2
Brief Description  cytochrome P450 family 26 subfamily B member 1
Description  This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
  • synonyms:
  • P450RAI2,
  • HGNC:20581,
  • RHFCA,
  • OTTHUMG00000129756,
  • uc002sih.3,
  • cytochrome P450 family 26 subfamily A member 1,
  • P450RAI-2,
  • CYP26A2,
  • cytochrome P450, family 26, subfamily B, polypeptide 1,
  • CYP26B1,
  • P450RAI-2,
  • NM_019885
  • identifiers:
  • 56603,
  • ENSG00000003137,
  • CYP26B1

Genome feature

Region: gene ? Length: 18625  
Location: 2:72129238-72147862 reverse strand Cyto location: 2p13.2


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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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Expression

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Other

937 SN Ps

5 Cross References

19 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results