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Gene : FMN2 Homo sapiens

Name  ? formin 2 Cytological Location  1q43
Brief Description  formin 2
Description  This gene is a member of the formin homology protein family. The encoded protein is thought to have essential roles in organization of the actin cytoskeleton and in cell polarity. This protein mediates the formation of an actin mesh that positions the spindle during oogenesis and also regulates the formation of actin filaments in the nucleus. This protein also forms a perinuclear actin/focal-adhesion system that regulates the shape and position of the nucleus during cell migration. Mutations in this gene have been associated with infertility and also with an autosomal recessive form of intellectual disability (MRT47). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Jul 2017]
  • synonyms:
  • uc010pyd.3,
  • AF218942,
  • NM_020066,
  • HGNC:14074,
  • OTTHUMG00000039883,
  • FMN2
  • identifiers:
  • 56776,
  • ENSG00000155816,
  • FMN2

Genome feature

Region: gene ? Length: 383305  
Location: 1:240091883-240475187 Cyto location: 1q43


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

Gene --> Proteins.

SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

791 SN Ps

5 Cross References

18 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results