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Gene : CD177 Homo sapiens

Name  ? CD177 molecule Cytological Location  19q13.31
Brief Description  CD177 molecule
Description  This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]
  • synonyms:
  • CD177 antigen,
  • NB1 GP,
  • NB1,
  • CD177,
  • HGNC:30072,
  • PRV-1,
  • PRV1,
  • HNA2A,
  • HNA2A,
  • NM_020406,
  • NB1,
  • PRV1,
  • HNA-2a,
  • AF146747,
  • OTTHUMG00000185320,
  • polycythemia rubra vera 1,
  • uc032hyu.2
  • identifiers:
  • 57126,
  • ENSG00000204936,
  • CD177

Genome feature

Region: gene ? Length: 12378  
Location: 19:43353686-43366063 Cyto location: 19q13.31

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Ontology

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3753 SN Ps

5 Cross References

15 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results