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Gene : BAD Homo sapiens

Name  ? BCL2 associated agonist of cell death Cytological Location  11q13.1
Brief Description  BCL2 associated agonist of cell death
Description  The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc001nzd.4,
  • AF021792,
  • NM_032989,
  • BAD,
  • BBC2,
  • BBC2,
  • BCL2L8,
  • BCL2L8,
  • OTTHUMG00000134302,
  • HGNC:936
  • identifiers:
  • 572,
  • ENSG00000002330,
  • BAD

Genome feature

Region: gene ? Length: 14877  
Location: 11:64269828-64284704 reverse strand Cyto location: 11q13.1

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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223 SN Ps

5 Cross References

16 Data Sets

4 Homologues

1 Located Features

97 Rna Seq Results