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Gene : DPP10 Homo sapiens

Name  ? dipeptidyl peptidase like 10 Cytological Location  2q14.1
Brief Description  dipeptidyl peptidase like 10
Description  This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • synonyms:
  • AY172661,
  • DPPY,
  • DPRP3,
  • HGNC:20823,
  • OTTHUMG00000153294,
  • DPL2,
  • dipeptidyl-peptidase 10,
  • DPP10,
  • DPPY,
  • DPL2,
  • uc002tla.3,
  • DPRP3,
  • NM_020868,
  • dipeptidyl-peptidase 10 (inactive),
  • dipeptidylpeptidase 10,
  • DPRP-3
  • identifiers:
  • 57628,
  • ENSG00000175497,
  • DPP10

Genome feature

Region: gene ? Length: 1403140  
Location: 2:114442641-115845780 Cyto location: 2q14.1


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

3753 SN Ps

5 Cross References

16 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results