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Gene : BAK1 Homo sapiens

Name  ? BCL2 antagonist/killer 1 Cytological Location  6p21.31
Brief Description  BCL2 antagonist/killer 1
Description  The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CDN1,
  • uc003oes.4,
  • OTTHUMG00000014530,
  • BCL2L7,
  • BCL2L7,
  • HGNC:949,
  • BAK,
  • BAK,
  • U23765,
  • BAK1,
  • CDN1,
  • NM_001188,
  • BCL2-antagonist/killer 1
  • identifiers:
  • 578,
  • ENSG00000030110,
  • BAK1

Genome feature

Region: gene ? Length: 7745  
Location: 6:33572552-33580296 reverse strand Cyto location: 6p21.31

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

16 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results