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Gene : G6PC2 Homo sapiens

Name  ? glucose-6-phosphatase catalytic subunit 2 Cytological Location  2q31.1
Brief Description  glucose-6-phosphatase catalytic subunit 2
Description  This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • synonyms:
  • IGRP,
  • glucose-6-phosphatase, catalytic, 2,
  • NM_021176,
  • AF283575,
  • uc002uem.4,
  • IGRP,
  • G6PC2,
  • OTTHUMG00000132182,
  • islet specific glucose 6 phosphatase catalytic subunit related protein,
  • HGNC:28906
  • identifiers:
  • 57818,
  • ENSG00000152254,
  • G6PC2

Genome feature

Region: gene ? Length: 8778  
Location: 2:168901223-168910000 Cyto location: 2q31.1


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Disease

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3753 SN Ps

4 Cross References

14 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results