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Gene : DNASE2B Homo sapiens

Name  ? deoxyribonuclease 2 beta Cytological Location  1p31.1-p22.3
Brief Description  deoxyribonuclease 2 beta
Description  The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • DLAD,
  • DNASE2B,
  • OTTHUMG00000009860,
  • uc001dju.2,
  • deoxyribonuclease II beta,
  • DLAD,
  • NM_021233,
  • AF274571,
  • HGNC:28875
  • identifiers:
  • 58511,
  • ENSG00000137976,

Genome feature

Region: gene ? Length: 17364  
Location: 1:84398532-84415895 Cyto location: 1p31.1-p22.3

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Gene Ontology Displayer

1 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



1 Pathways

906 SN Ps

5 Cross References

16 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results